By Archie W. Prestayko
Comprised of 39 chapters, this publication starts with a preclinical evaluation of cisplatin, targeting its mechanism of motion, pharmacology, antitumor job, analogs, and toxicity. The dialogue then turns to the consequences of cisplatin on DNA and the prospective relationships to cytotoxicity and mutagenicity in mammalian cells; deadly job of platinum compounds together with pyrimidine derivatives; and ultrastructural results of cisplatin. next chapters specialise in the reason of blend chemotherapy; poisonous unwanted effects of platinum analogs; radiopharmacokinetics of cisplatin; and using cisplatin for the therapy of malignancies akin to ovarian melanoma and complicated adenocarcinoma of the prostate.
This monograph should be invaluable to oncologists and pharmacologists.
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Additional resources for Cisplatin: Current Status and New Developments
Cisplatin: Current Status and New Developments by Archie W. Prestayko