Organic Chemistry

New PDF release: Copper-Catalyzed Asymmetric Synthesis

By Alexandre Alexakis,Norbert Krause,Simon Woodward

This e-book displays the expanding curiosity one of the chemical artificial neighborhood within the sector of uneven copper-catalyzed reactions, and introduces readers to the newest, most vital advancements within the field.

The contents are equipped in response to response kind and canopy mechanistic and spectroscopic points in addition to purposes within the synthesis of typical items. a complete bankruptcy is dedicated to realizing how fundamental organometallics engage with copper to supply selective catalysts for allylic substitution and conjugate addition, either one of that are taken care of in separate chapters. one other is dedicated to the range of substrates and experimental protocols, whereas a whole bankruptcy covers the use on non-carbon nucleophiles. different chapters take care of less-known reactions, akin to carbometallation or the additions to imines and comparable structures, whereas the extra demonstrated reactions cyclopropanation and aziridination in addition to using copper (II) Lewis acids are warranted their very own designated chapters. extra chapters difficulty the tactics concerned, as decided by means of mechanistic stories. eventually, an entire bankruptcy is dedicated to the substitute applications.

this is often crucial examining for researchers at educational associations and execs at pharmaceutical or agrochemical companies.

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Copper-Catalyzed Asymmetric Synthesis by Alexandre Alexakis,Norbert Krause,Simon Woodward


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